Retargeting Vesicular Stomatitis Virus Using Measles Virus Envelope Glycoproteins
نویسندگان
چکیده
منابع مشابه
Vesicular Stomatitis Virus
Defective particles were the major product after undiluted passage of certain temperature-sensitive (ts) mutants of the Indiana C strain of vesicular stomatitis virus in BHK-21 cells at the permissive temperature (31 C). Essentially homogeneous preparations of defective particles were obtained with the wild-type and individual ts mutants. The defective particles associated with some of the ts m...
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Vesicular stomatitis virus (VSV) forms pseudotypes with envelope components of reticuloendotheliosis virus (REV). The VSV pseudotype possesses the limited host range and antigenic properties of REV. Approximately 70% of the VSV, Indiana serotype, and 45% of VSV, New Jersey serotype, produced from the REV strain T-transformed chicken bone marrow cells contain mixed envelope components of both VS...
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In recent years a major thrust in immunology has been to clarify the morphological, surface, and functional properties of the complex populations comprising the lymphoid cell series. At the core of the problem is the mechanism of lymphocyte "activation," the process by which specific antigens or nonspecific agents stimulate resting lymphocytes to transform morphologically (1-5) and to exhibit a...
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To develop surrogate viruses for hepatitis C virus (HCV), we previously produced recombinant vesicular stomatitis viruses (rVSVs) lacking glycoprotein G but instead expressing chimeric HCV E1/E2 fused to G. These rVSVs were not infectious in HCV-susceptible hepatoma cells. In this study, to develop an infectious surrogate HCV based on an rVSV (vesicular stomatitis virus [VSV]/HCV), we generated...
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ژورنال
عنوان ژورنال: Human Gene Therapy
سال: 2012
ISSN: 1043-0342,1557-7422
DOI: 10.1089/hum.2011.146